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Silibinin Effect on Methotrexate-Induced Hepatotoxicity in Rats

OBJECTIVE: Hepatotoxicity is one of the major side effects of methotrexate and limits its use. In this study, we investigated the hepatoprotective effect of silibinin and the role of oxidative stress markers and cytokines on high-dose methotrexate-induced hepatotoxicity in rats. MATERIALS AND METHOD...

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Detalles Bibliográficos
Autores principales:	Yanaşoğlu, Emine, Büyükavcı, Mustafa, Çetinkaya, Ayhan, Turan, Gupse, Köroğlu, Mehmet, Yazar, Hayrullah, Büyükokuroğlu, Mehmet Emin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Atatürk University School of Medicine 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797782/ https://www.ncbi.nlm.nih.gov/pubmed/35971282 http://dx.doi.org/10.5152/eurasianjmed.2022.20371

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