Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer

BACKGROUND: Extracellular vesicles secreted by tumor cells contain double-stranded DNA called extracellular vesicle DNA (evDNA). EvDNA is genomic DNA that reflects cancer driver mutations. However, the significance of evDNA analysis in the diagnosis and surveillance of colon cancer remains unclear....

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Detalles Bibliográficos
Autores principales: Choi, Jeesoo, Cho, Ho Yeon, Jeon, Jeongseok, Kim, Kyung-A, Han, Yoon Dae, Ahn, Joong Bae, Wortzel, Inbal, Lyden, David, Kim, Han Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797818/
https://www.ncbi.nlm.nih.gov/pubmed/36591510
http://dx.doi.org/10.3389/fonc.2022.1067210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797818/
https://www.ncbi.nlm.nih.gov/pubmed/36591510
http://dx.doi.org/10.3389/fonc.2022.1067210

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