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Spatial heterogeneity of infiltrating T cells in high-grade serous ovarian cancer revealed by multi-omics analysis

Tumor-infiltrating lymphocytes (TILs), especially CD8(+) TILs, represent a favorable prognostic factor in high-grade serous ovarian cancer (HGSOC) and other tumor lineages. Here, we analyze the spatial heterogeneity of different TIL subtypes in HGSOC. We integrated RNA sequencing, whole-genome seque...

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Detalles Bibliográficos
Autores principales:	Yang, Bin, Li, Xiong, Zhang, Wei, Fan, Junpeng, Zhou, Yong, Li, Wenting, Yin, Jingjing, Yang, Xiaohang, Guo, Ensong, Li, Xi, Fu, Yu, Liu, Si, Hu, Dianxing, Qin, Xu, Dou, Yingyu, Xiao, Rourou, Lu, Funian, Wang, Zizhuo, Qin, Tianyu, Wang, Wei, Zhang, Qinghua, Li, Shuaicheng, Ma, Ding, Mills, Gordon B., Chen, Gang, Sun, Chaoyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798026/ https://www.ncbi.nlm.nih.gov/pubmed/36543113 http://dx.doi.org/10.1016/j.xcrm.2022.100856

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