Imbalance in the ratio between mineralocorticoid and glucocorticoid receptors and neurodegeneration in the dentate gyrus of aged dogs

BACKGROUND AND AIM: Cortisol binds to mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) found in the hippocampus. The balanced expression of these receptors is essential to neuronal survival as MR and GR activations have antiapoptotic and proapoptotic effects, respectively. Given the...

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Detalles Bibliográficos
Autores principales: Szriber, Shirley Jaqueline, Novaes, Leonardo Santana, Santos, Nilton Barreto Dos, Munhoz, Carolina Demarchi, Leite-Dellova, Deise Carla Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798053/
https://www.ncbi.nlm.nih.gov/pubmed/36590120
http://dx.doi.org/10.14202/vetworld.2022.2543-2550

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