HRD-related morphology discovery in breast cancer by controlling for confounding factors

Lazard et al.(1) predict homologous recombination deficiency from hematoxylin and eosin-stained slides of breast cancer tissue using deep learning. By controlling for technical artifacts on a curated dataset, the model puts forward novel HRD-related morphologies in luminal breast cancers.

Detalles Bibliográficos
Autores principales: Schirris, Yoni, Horlings, Hugo Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Preview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798077/
https://www.ncbi.nlm.nih.gov/pubmed/36543118
http://dx.doi.org/10.1016/j.xcrm.2022.100873
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author Schirris, Yoni
Horlings, Hugo Mark
author_facet Schirris, Yoni
Horlings, Hugo Mark
author_sort Schirris, Yoni
collection PubMed
description Lazard et al.(1) predict homologous recombination deficiency from hematoxylin and eosin-stained slides of breast cancer tissue using deep learning. By controlling for technical artifacts on a curated dataset, the model puts forward novel HRD-related morphologies in luminal breast cancers.
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spelling pubmed-97980772022-12-30 HRD-related morphology discovery in breast cancer by controlling for confounding factors Schirris, Yoni Horlings, Hugo Mark Cell Rep Med Preview Lazard et al.(1) predict homologous recombination deficiency from hematoxylin and eosin-stained slides of breast cancer tissue using deep learning. By controlling for technical artifacts on a curated dataset, the model puts forward novel HRD-related morphologies in luminal breast cancers. Elsevier 2022-12-20 /pmc/articles/PMC9798077/ /pubmed/36543118 http://dx.doi.org/10.1016/j.xcrm.2022.100873 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preview
Schirris, Yoni
Horlings, Hugo Mark
HRD-related morphology discovery in breast cancer by controlling for confounding factors
title HRD-related morphology discovery in breast cancer by controlling for confounding factors
title_full HRD-related morphology discovery in breast cancer by controlling for confounding factors
title_fullStr HRD-related morphology discovery in breast cancer by controlling for confounding factors
title_full_unstemmed HRD-related morphology discovery in breast cancer by controlling for confounding factors
title_short HRD-related morphology discovery in breast cancer by controlling for confounding factors
title_sort hrd-related morphology discovery in breast cancer by controlling for confounding factors
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798077/
https://www.ncbi.nlm.nih.gov/pubmed/36543118
http://dx.doi.org/10.1016/j.xcrm.2022.100873
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