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Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection

BACKGROUND: Identifying immune processes required for liver-stage sterilizing immunity to malaria remains an open problem. The IMRAS trial comprised 5x immunizations with radiation-attenuated sporozoites resulting in 55% protection from subsequent challenge. METHODS: To identify correlates of vaccin...

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Detalles Bibliográficos
Autores principales:	Duffy, Fergal J., Hertoghs, Nina, Du, Ying, Neal, Maxwell L., Oyong, Damian, McDermott, Suzanne, Minkah, Nana, Carnes, Jason, Schwedhelm, Katharine V., McElrath, M. Juliana, De Rosa, Stephen C., Newell, Evan, Aitchison, John D., Stuart, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798120/ https://www.ncbi.nlm.nih.gov/pubmed/36591224 http://dx.doi.org/10.3389/fimmu.2022.1042741

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