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Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report

White cord syndrome refers to an emerging neurological dysfunction occurring after spinal decompression surgery with hyperenhancing changes on T2-weighted magnetic resonance imaging (T2WI). The pathophysiological mechanism is hypothesized to be an ischemia-reperfusion injury following chronic ischem...

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Autores principales: Lei, Chang-Zhen, Gong, Dao-Jun, Zhou, Yang-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798147/
https://www.ncbi.nlm.nih.gov/pubmed/36605533
http://dx.doi.org/10.3892/etm.2022.11770
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author Lei, Chang-Zhen
Gong, Dao-Jun
Zhou, Yang-Fan
author_facet Lei, Chang-Zhen
Gong, Dao-Jun
Zhou, Yang-Fan
author_sort Lei, Chang-Zhen
collection PubMed
description White cord syndrome refers to an emerging neurological dysfunction occurring after spinal decompression surgery with hyperenhancing changes on T2-weighted magnetic resonance imaging (T2WI). The pathophysiological mechanism is hypothesized to be an ischemia-reperfusion injury following chronic ischemic spinal cord decompression. A 54-year-old man was admitted to Jinhua Municipal Central Hospital with complaints of numbness and weakness in the extremities and swelling in the neck. MRI showed degeneration and herniation of the C4-C7 intervertebral discs. The patient underwent anterior cervical corpectomy and fusion (ACCF). On the 7th postoperative day, the patient reappeared with weakness of the limbs. Physical examination revealed paralysis. Emergency MRI suggested T2 high signal myelopathy and emergency surgery was performed following the diagnosis of white cord syndrome. Following the operation, the patient's neurological system gradually improved. The motor ability and sensory function of the extremities recovered at 7-month follow-up. Spine surgeons should be aware of this serious complication. The present case serves to provide experience for clinical treatment and diagnosis and encourage research into its pathophysiology.
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spelling pubmed-97981472023-01-04 Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report Lei, Chang-Zhen Gong, Dao-Jun Zhou, Yang-Fan Exp Ther Med Case Report White cord syndrome refers to an emerging neurological dysfunction occurring after spinal decompression surgery with hyperenhancing changes on T2-weighted magnetic resonance imaging (T2WI). The pathophysiological mechanism is hypothesized to be an ischemia-reperfusion injury following chronic ischemic spinal cord decompression. A 54-year-old man was admitted to Jinhua Municipal Central Hospital with complaints of numbness and weakness in the extremities and swelling in the neck. MRI showed degeneration and herniation of the C4-C7 intervertebral discs. The patient underwent anterior cervical corpectomy and fusion (ACCF). On the 7th postoperative day, the patient reappeared with weakness of the limbs. Physical examination revealed paralysis. Emergency MRI suggested T2 high signal myelopathy and emergency surgery was performed following the diagnosis of white cord syndrome. Following the operation, the patient's neurological system gradually improved. The motor ability and sensory function of the extremities recovered at 7-month follow-up. Spine surgeons should be aware of this serious complication. The present case serves to provide experience for clinical treatment and diagnosis and encourage research into its pathophysiology. D.A. Spandidos 2022-12-14 /pmc/articles/PMC9798147/ /pubmed/36605533 http://dx.doi.org/10.3892/etm.2022.11770 Text en Copyright: © Lei et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Case Report
Lei, Chang-Zhen
Gong, Dao-Jun
Zhou, Yang-Fan
Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report
title Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report
title_full Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report
title_fullStr Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report
title_full_unstemmed Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report
title_short Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report
title_sort late‑onset white cord syndrome following anterior cervical discectomy and fusion: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798147/
https://www.ncbi.nlm.nih.gov/pubmed/36605533
http://dx.doi.org/10.3892/etm.2022.11770
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