Cryopreserved anti-CD22 and bispecific anti-CD19/22 CAR T cells are as effective as freshly infused cells

Cryopreservation of chimeric antigen receptor (CAR) T cells facilitates shipment, timing of infusions, and storage of subsequent doses. However, reports on the impact of cryopreservation on CAR T cell efficacy have been mixed. We retrospectively compared clinical outcomes between patients who receiv...

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Detalles Bibliográficos
Autores principales: Dreyzin, Alexandra, Panch, Sandhya R., Shalabi, Haneen, Yates, Bonnie, Highfill, Steven L., Jin, Ping, Stroncek, David, Shah, Nirali N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798176/
https://www.ncbi.nlm.nih.gov/pubmed/36620075
http://dx.doi.org/10.1016/j.omtm.2022.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798176/
https://www.ncbi.nlm.nih.gov/pubmed/36620075
http://dx.doi.org/10.1016/j.omtm.2022.12.004

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