Comparison of busulfan and total body irradiation conditioning on hematopoietic clonal dynamics following lentiviral gene transfer in rhesus macaques

The clonal dynamics following hematopoietic stem progenitor cell (HSPC) transplantation with busulfan conditioning are of great interest to the development of HSPC gene therapies. Compared with total body irradiation (TBI), busulfan is less toxic and more clinically relevant. We used a genetic barco...

Descripción completa

Detalles Bibliográficos
Autores principales: Abraham, Diana M., Lozano, Richard J., Guitart, Xavi, Liang, Jialiu A., Mortlock, Ryland D., Espinoza, Diego A., Fan, Xing, Krouse, Allen, Bonifacino, Aylin, Hong, So Gun, Singh, Komudi, Tisdale, John F., Wu, Chuanfeng, Dunbar, Cynthia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798201/
https://www.ncbi.nlm.nih.gov/pubmed/36620072
http://dx.doi.org/10.1016/j.omtm.2022.12.001

Ejemplares similares

Ejemplares similares