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The role of heat shock proteins in preventing amyloid toxicity

The oligomerization of monomeric proteins into large, elongated, β-sheet-rich fibril structures (amyloid), which results in toxicity to impacted cells, is highly correlated to increased age. The concomitant decrease of the quality control system, composed of chaperones, ubiquitin-proteasome system a...

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Detalles Bibliográficos
Autores principales: Törner, Ricarda, Kupreichyk, Tatsiana, Hoyer, Wolfgang, Boisbouvier, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798239/
https://www.ncbi.nlm.nih.gov/pubmed/36589244
http://dx.doi.org/10.3389/fmolb.2022.1045616

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