Cargando…

Cardia function-preserving surgery and anti-reflux anastomotic method after proximal gastrectomy for gastric cancer: Current status and future perspectives

The incidence and mortality of gastric cancer ranked 5th and 3rd worldwide, respectively, in 2018, and the incidence of gastroesophageal junction adenocarcinoma increased over the past 40 years. Radical resection and lymph node dissection is the preferred treatment for gastric cancer. Proximal gastr...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Li, Liu, Zheng-hui, Cai, Xu-fan, Jiang, Qi-tao, Mou, Yi-ping, Wang, Yuan-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798307/
https://www.ncbi.nlm.nih.gov/pubmed/36591467
http://dx.doi.org/10.3389/fonc.2022.1000719
_version_ 1784860880405528576
author Li, Li
Liu, Zheng-hui
Cai, Xu-fan
Jiang, Qi-tao
Mou, Yi-ping
Wang, Yuan-Yu
author_facet Li, Li
Liu, Zheng-hui
Cai, Xu-fan
Jiang, Qi-tao
Mou, Yi-ping
Wang, Yuan-Yu
author_sort Li, Li
collection PubMed
description The incidence and mortality of gastric cancer ranked 5th and 3rd worldwide, respectively, in 2018, and the incidence of gastroesophageal junction adenocarcinoma increased over the past 40 years. Radical resection and lymph node dissection is the preferred treatment for gastric cancer. Proximal gastrectomy or total gastrectomy is usually performed for gastroesophageal junction adenocarcinoma and upper gastric cancer. Owing to the resection of the cardia structures, the incidence of reflux esophagitis increases significantly after proximal gastrectomy and total gastrectomy, resulting in poor postoperative quality of life. To reduce the incidence of reflux esophagitis and improve patients’ postoperative quality of life, various methods to preserve the function of the cardia or to perform anti-reflux reconstruction have emerged. In this manuscript, we systematically introduced the advantages and problems of various anti-reflux anastomotic method after proximal gastrectomy, and cardia-preserving gastrectomy including endoscopic resection (ER), local gastrectomy by gastroscopy combined with laparoscopy, segmental gastrectomy, subtotal gastrectomy, and cardia-preserving radical gastrectomy. Cardia-preserving radical gastrectomy has the advantage of more thorough lymph node dissection and wider indications than those for subtotal gastrectomy. However, the clinical efficacy of cardia-preserving radical gastrectomy requires verification in prospective and controlled clinical trials. Cardia-preserving radical gastrectomy is a promising approach as one of the more reasonable anti-reflux surgeries.
format Online
Article
Text
id pubmed-9798307
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-97983072022-12-30 Cardia function-preserving surgery and anti-reflux anastomotic method after proximal gastrectomy for gastric cancer: Current status and future perspectives Li, Li Liu, Zheng-hui Cai, Xu-fan Jiang, Qi-tao Mou, Yi-ping Wang, Yuan-Yu Front Oncol Oncology The incidence and mortality of gastric cancer ranked 5th and 3rd worldwide, respectively, in 2018, and the incidence of gastroesophageal junction adenocarcinoma increased over the past 40 years. Radical resection and lymph node dissection is the preferred treatment for gastric cancer. Proximal gastrectomy or total gastrectomy is usually performed for gastroesophageal junction adenocarcinoma and upper gastric cancer. Owing to the resection of the cardia structures, the incidence of reflux esophagitis increases significantly after proximal gastrectomy and total gastrectomy, resulting in poor postoperative quality of life. To reduce the incidence of reflux esophagitis and improve patients’ postoperative quality of life, various methods to preserve the function of the cardia or to perform anti-reflux reconstruction have emerged. In this manuscript, we systematically introduced the advantages and problems of various anti-reflux anastomotic method after proximal gastrectomy, and cardia-preserving gastrectomy including endoscopic resection (ER), local gastrectomy by gastroscopy combined with laparoscopy, segmental gastrectomy, subtotal gastrectomy, and cardia-preserving radical gastrectomy. Cardia-preserving radical gastrectomy has the advantage of more thorough lymph node dissection and wider indications than those for subtotal gastrectomy. However, the clinical efficacy of cardia-preserving radical gastrectomy requires verification in prospective and controlled clinical trials. Cardia-preserving radical gastrectomy is a promising approach as one of the more reasonable anti-reflux surgeries. Frontiers Media S.A. 2022-12-15 /pmc/articles/PMC9798307/ /pubmed/36591467 http://dx.doi.org/10.3389/fonc.2022.1000719 Text en Copyright © 2022 Li, Liu, Cai, Jiang, Mou and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Li, Li
Liu, Zheng-hui
Cai, Xu-fan
Jiang, Qi-tao
Mou, Yi-ping
Wang, Yuan-Yu
Cardia function-preserving surgery and anti-reflux anastomotic method after proximal gastrectomy for gastric cancer: Current status and future perspectives
title Cardia function-preserving surgery and anti-reflux anastomotic method after proximal gastrectomy for gastric cancer: Current status and future perspectives
title_full Cardia function-preserving surgery and anti-reflux anastomotic method after proximal gastrectomy for gastric cancer: Current status and future perspectives
title_fullStr Cardia function-preserving surgery and anti-reflux anastomotic method after proximal gastrectomy for gastric cancer: Current status and future perspectives
title_full_unstemmed Cardia function-preserving surgery and anti-reflux anastomotic method after proximal gastrectomy for gastric cancer: Current status and future perspectives
title_short Cardia function-preserving surgery and anti-reflux anastomotic method after proximal gastrectomy for gastric cancer: Current status and future perspectives
title_sort cardia function-preserving surgery and anti-reflux anastomotic method after proximal gastrectomy for gastric cancer: current status and future perspectives
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798307/
https://www.ncbi.nlm.nih.gov/pubmed/36591467
http://dx.doi.org/10.3389/fonc.2022.1000719
work_keys_str_mv AT lili cardiafunctionpreservingsurgeryandantirefluxanastomoticmethodafterproximalgastrectomyforgastriccancercurrentstatusandfutureperspectives
AT liuzhenghui cardiafunctionpreservingsurgeryandantirefluxanastomoticmethodafterproximalgastrectomyforgastriccancercurrentstatusandfutureperspectives
AT caixufan cardiafunctionpreservingsurgeryandantirefluxanastomoticmethodafterproximalgastrectomyforgastriccancercurrentstatusandfutureperspectives
AT jiangqitao cardiafunctionpreservingsurgeryandantirefluxanastomoticmethodafterproximalgastrectomyforgastriccancercurrentstatusandfutureperspectives
AT mouyiping cardiafunctionpreservingsurgeryandantirefluxanastomoticmethodafterproximalgastrectomyforgastriccancercurrentstatusandfutureperspectives
AT wangyuanyu cardiafunctionpreservingsurgeryandantirefluxanastomoticmethodafterproximalgastrectomyforgastriccancercurrentstatusandfutureperspectives