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Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS

The secreted malarial protein, Cell-Traversal protein for Ookinetes and Sporozoites (CelTOS), is highly conserved among Plasmodium species, and plays a role in the invasion of mosquito midgut cells and hepatocytes in the vertebrate host. CelTOS was identified as a potential protective antigen based...

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Detalles Bibliográficos
Autores principales: Waghela, Ishita N., Mallory, Katherine L., Taylor, Justin A., Schneider, Cosette G., Savransky, Tatyana, Janse, Chris J., Lin, Paulo J. C., Tam, Ying K., Weissman, Drew, Angov, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798330/
https://www.ncbi.nlm.nih.gov/pubmed/36591298
http://dx.doi.org/10.3389/fimmu.2022.1026052