Cargando…
Immunoproteasome inhibition attenuates experimental psoriasis
INTRODUCTION: Psoriasis is an autoimmune skin disease associated with multiple comorbidities. The immunoproteasome is a special form of the proteasome expressed in cells of hematopoietic origin. METHODS: The therapeutic use of ONX 0914, a selective inhibitor of the immunoproteasome, was investigated...
Autores principales: | del Rio Oliva, Marta, Mellett, Mark, Basler, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798438/ https://www.ncbi.nlm.nih.gov/pubmed/36591277 http://dx.doi.org/10.3389/fimmu.2022.1075615 |
Ejemplares similares
-
Immunoproteasome Inhibition Impairs T and B Cell Activation by Restraining ERK Signaling and Proteostasis
por: Schmidt, Christian, et al.
Publicado: (2018) -
Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis
por: Basler, Michael, et al.
Publicado: (2014) -
Immunoproteasome Inhibition Reduces the T Helper 2 Response in Mouse Models of Allergic Airway Inflammation
por: Oliveri, Franziska, et al.
Publicado: (2022) -
On the Role of the Immunoproteasome in Protein Homeostasis
por: Basler, Michael, et al.
Publicado: (2021) -
Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice
por: Mundt, Sarah, et al.
Publicado: (2016)