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Interleukin-3 is associated with sTREM2 and mediates the correlation between amyloid-β and tau pathology in Alzheimer’s disease

BACKGROUND: Dysfunction of glial cell communication is involved in Alzheimer’s disease (AD) pathogenesis, and the recent study reported that astrocytic secreted interleukin-3 (IL-3) participated in astrocyte–microglia crosstalk and restricted AD pathology in mice, but the effect of IL-3 on the patho...

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Detalles Bibliográficos
Autores principales:	Wang, Zhi-Bo, Ma, Ya-Hui, Sun, Yan, Tan, Lan, Wang, Hui-Fu, Yu, Jin-Tai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798566/ https://www.ncbi.nlm.nih.gov/pubmed/36578067 http://dx.doi.org/10.1186/s12974-022-02679-5

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