Sushi domain-containing protein 4 binds to epithelial growth factor receptor and initiates autophagy in an EGFR phosphorylation independent manner

BACKGROUND: Sushi domain-containing protein 4 (SUSD4) is a recently discovered protein with unknown cellular functions. We previously revealed that SUSD4 can act as complement inhibitor and as a potential tumor suppressor. METHODS: In a syngeneic mouse model of breast cancer, tumors expressing SUSD4...

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Detalles Bibliográficos
Autores principales: Papadakos, Konstantinos S., Ekström, Alexander, Slipek, Piotr, Skourti, Eleni, Reid, Steven, Pietras, Kristian, Blom, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798675/
https://www.ncbi.nlm.nih.gov/pubmed/36578014
http://dx.doi.org/10.1186/s13046-022-02565-1

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