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Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway

BACKGROUND: Cytokines secreted in the tumor microenvironment function in cancer cachexia (CC), a common clinicopathological syndrome associated with adipocyte wasting and skeletal muscle atrophy. Extracellular vesicles (EVs) secreted by cancer cells actively engage in inter-tissue communication; EVs...

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Detalles Bibliográficos
Autores principales:	Xiong, Hairong, Ye, Jiaxin, Xie, Kairu, Hu, Wenjun, Xu, Ning, Yang, Hongmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798689/ https://www.ncbi.nlm.nih.gov/pubmed/36581870 http://dx.doi.org/10.1186/s12944-022-01755-2

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