SAMHD1 silencing cooperates with radiotherapy to enhance anti-tumor immunity through IFI16-STING pathway in lung adenocarcinoma

BACKGROUND: Sterile alpha motif domain and histidine-aspartate domain-containing protein 1 (SAMHD1) is a DNA end resection factor, which is involved in DNA damage repair and innate immunity. However, the role of SAMHD1 in anti-tumor immunity is still unknown. This study investigated the effects of S...

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Detalles Bibliográficos
Autores principales: Li, Yangyi, Gao, Yuke, Jiang, Xueping, Cheng, Yajie, Zhang, Jianguo, Xu, Liexi, Liu, Xinyu, Huang, Zhengrong, Xie, Conghua, Gong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798699/
https://www.ncbi.nlm.nih.gov/pubmed/36578072
http://dx.doi.org/10.1186/s12967-022-03844-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798699/
https://www.ncbi.nlm.nih.gov/pubmed/36578072
http://dx.doi.org/10.1186/s12967-022-03844-3

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