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SAMHD1 silencing cooperates with radiotherapy to enhance anti-tumor immunity through IFI16-STING pathway in lung adenocarcinoma

BACKGROUND: Sterile alpha motif domain and histidine-aspartate domain-containing protein 1 (SAMHD1) is a DNA end resection factor, which is involved in DNA damage repair and innate immunity. However, the role of SAMHD1 in anti-tumor immunity is still unknown. This study investigated the effects of S...

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Detalles Bibliográficos
Autores principales:	Li, Yangyi, Gao, Yuke, Jiang, Xueping, Cheng, Yajie, Zhang, Jianguo, Xu, Liexi, Liu, Xinyu, Huang, Zhengrong, Xie, Conghua, Gong, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798699/ https://www.ncbi.nlm.nih.gov/pubmed/36578072 http://dx.doi.org/10.1186/s12967-022-03844-3

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