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Aβ42 oligomer-specific antibody ALZ-201 reduces the neurotoxicity of Alzheimer’s disease brain extracts

BACKGROUND: In Alzheimer’s disease (AD), amyloid-β 1–42 (Aβ42) neurotoxicity stems mostly from its soluble oligomeric aggregates. Studies of such aggregates have been hampered by the lack of oligomer-specific research tools and their intrinsic instability and heterogeneity. Here, we developed a mono...

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Detalles Bibliográficos
Autores principales:	Sandberg, Anders, Berenjeno-Correa, Ernesto, Rodriguez, Rosa Crespo, Axenhus, Michael, Weiss, Sophia Schedin, Batenburg, Kevin, Hoozemans, Jeroen J. M., Tjernberg, Lars O., Scheper, Wiep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798723/ https://www.ncbi.nlm.nih.gov/pubmed/36578089 http://dx.doi.org/10.1186/s13195-022-01141-1

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