Structural basis for the assembly of the type V CRISPR-associated transposon complex

CRISPR-Cas systems have been co-opted by Tn7-like transposable elements to direct RNA-guided transposition. Type V-K CRISPR-associated transposons rely on the concerted activities of the pseudonuclease Cas12k, the AAA+ ATPase TnsC, the Zn-finger protein TniQ, and the transposase TnsB. Here we presen...

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Detalles Bibliográficos
Autores principales: Schmitz, Michael, Querques, Irma, Oberli, Seraina, Chanez, Christelle, Jinek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798831/
https://www.ncbi.nlm.nih.gov/pubmed/36435179
http://dx.doi.org/10.1016/j.cell.2022.11.009

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