Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has highlighted the need for vaccines that not only prevent disease but also prevent transmission. Parenteral vaccines induce robust systemic immunity but poor immunity at the respiratory mucosa. We developed a vaccine strateg...

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Detalles Bibliográficos
Autores principales: Mao, Tianyang, Israelow, Benjamin, Peña-Hernández, Mario A., Suberi, Alexandra, Zhou, Liqun, Luyten, Sophia, Reschke, Melanie, Dong, Huiping, Homer, Robert J., Saltzman, W. Mark, Iwasaki, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798903/
https://www.ncbi.nlm.nih.gov/pubmed/36302057
http://dx.doi.org/10.1126/science.abo2523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798903/
https://www.ncbi.nlm.nih.gov/pubmed/36302057
http://dx.doi.org/10.1126/science.abo2523

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