Properties and Activity of Peptide Derivatives of ACE2 Cellular Receptor and Their Interaction with SARS-CoV-2 S Protein Receptor-Binding Domain

The aim of this work was to design and characterize peptides based on the α-helices h1 and h2 of the ACE2 receptor, forming the interaction interface between the receptor-binding domain (RBD) of the SARS-CoV-2 S protein and the cellular ACE2 receptor. Monomeric and heterodimeric peptides connected b...

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Detalles Bibliográficos
Autores principales: Sidorova, M. V., Bibilashvili, R. S., Avdeev, D. V., Kozhokar, U. S., Palkeeva, M. E., Ovchinnikov, M. V., Molokoedov, A. S., Shirokov, D. A., Semyonova, A. V., Uvarova, V. I., Kulyaev, P. O., Khvatov, E. V., Ignatova, A. A., Feofanov, A. V., Osolodkin, D. I., Porozov, Yu. B., Kozlovskaya, L. I., Ishmukhametov, A. A., Parfyonova, Ye. V., Egorov, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2022
Materias:
Biochemistry, Biophysics, and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798946/
https://www.ncbi.nlm.nih.gov/pubmed/36580213
http://dx.doi.org/10.1134/S1607672922060126

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