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Cerebral Malaria and Neuronal Implications of Plasmodium Falciparum Infection: From Mechanisms to Advanced Models (Adv. Sci. 36/2022)

Plasmodium falciparum Infection Cerebral malaria is the most severe complication caused by the malaria parasite P. falciparum. In article number 2202944, Oscar Bate Akide Ndunge, Nicole Kilian, and Mootaz M. Salman review the pathogenic mechanisms that underlie the development of this fatal conditio...

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Detalles Bibliográficos
Autores principales: Akide Ndunge, Oscar Bate, Kilian, Nicole, Salman, Mootaz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798958/
http://dx.doi.org/10.1002/advs.202270228
Descripción
Sumario:Plasmodium falciparum Infection Cerebral malaria is the most severe complication caused by the malaria parasite P. falciparum. In article number 2202944, Oscar Bate Akide Ndunge, Nicole Kilian, and Mootaz M. Salman review the pathogenic mechanisms that underlie the development of this fatal condition. Moreover, they discuss the current understanding and recent developments in diagnostic and treatment methods as well as advanced models to study and eventually tackle this devastating disease using organ‐on‐a‐chip and humanised systems. [Image: see text]