ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK

Hyperactivation of Bruton’s tyrosine kinase (BTK) or interleukin-2-inducible T cell kinase (ITK) has been attributed to the pathogenesis of B-cell lymphoma or T-cell leukemia, respectively, which suggests that Bruton’s tyrosine kinase and interleukin-2-inducible T cell kinase are critical targets fo...

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Detalles Bibliográficos
Autores principales: Song, Peiran, Bai, Gang, Chan, Shingpan, Zhang, Tao, Tong, Linjiang, Su, Yi, Shen, Yanyan, Chen, Yi, Liu, Yingqiang, Lai, Mengzhen, Ning, Yi, Tang, Haotian, Fang, Yan, Ding, Ke, Ding, Jian, Xie, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799096/
https://www.ncbi.nlm.nih.gov/pubmed/36588692
http://dx.doi.org/10.3389/fphar.2022.1071114

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