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The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

COVID-19 convalescent plasmas (CCPs) are chosen for plasma therapy based on neutralizing titers and anti-Spike immunoglobulin levels. However, CCP characteristics that promote SARS-CoV-2 control are complex and incompletely defined. Using an in vivo imaging approach, we demonstrate that CCPs with lo...

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Detalles Bibliográficos
Autores principales: Ullah, Irfan, Beaudoin-Bussières, Guillaume, Symmes, Kelly, Cloutier, Marc, Ducas, Eric, Tauzin, Alexandra, Laumaea, Annemarie, Grunst, Michael W., Dionne, Katrina, Richard, Jonathan, Bégin, Philippe, Mothes, Walther, Kumar, Priti, Bazin, Renée, Finzi, Andrés, Uchil, Pradeep D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799175/
https://www.ncbi.nlm.nih.gov/pubmed/36584683
http://dx.doi.org/10.1016/j.xcrm.2022.100893

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