TLR7 agonism accelerates disease in a mouse model of primary Sjögren’s syndrome and drives expansion of T-bet(+) B cells

Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by chronic inflammation of exocrine tissue, resulting in loss of tears and saliva. Patients also experience many extra-glandular disease manifestations. Treatment for pSS is palliative, and there are currently no treatme...

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Detalles Bibliográficos
Autores principales: Punnanitinont, Achamaporn, Kasperek, Eileen M., Kiripolsky, Jeremy, Zhu, Chengsong, Miecznikowski, Jeffrey C., Kramer, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799719/
https://www.ncbi.nlm.nih.gov/pubmed/36591307
http://dx.doi.org/10.3389/fimmu.2022.1034336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799719/
https://www.ncbi.nlm.nih.gov/pubmed/36591307
http://dx.doi.org/10.3389/fimmu.2022.1034336

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