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Oral biopsies in a Portuguese population: A 20-year clinicopathological study in a university clinic

BACKGROUND: Performing a biopsy is very important in oral medicine and the anatomopathological examination is fundamental to obtain or to confirm the diagnosis in oral and maxillofacial pathology. The purpose of this study is to analyse the frequency and characteristic patterns of biopsied oromaxill...

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Autores principales: de Almeida, Cláudia G., Freitas, Filipe, Francisco, Helena, Marques, João A., Caramês, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799996/
https://www.ncbi.nlm.nih.gov/pubmed/36601247
http://dx.doi.org/10.4317/jced.59688
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author de Almeida, Cláudia G.
Freitas, Filipe
Francisco, Helena
Marques, João A.
Caramês, João
author_facet de Almeida, Cláudia G.
Freitas, Filipe
Francisco, Helena
Marques, João A.
Caramês, João
author_sort de Almeida, Cláudia G.
collection PubMed
description BACKGROUND: Performing a biopsy is very important in oral medicine and the anatomopathological examination is fundamental to obtain or to confirm the diagnosis in oral and maxillofacial pathology. The purpose of this study is to analyse the frequency and characteristic patterns of biopsied oromaxillofacial lesions in a Portuguese population. MATERIAL AND METHODS: A descriptive statistical analysis of the data from the anatomopathological reports of the biopsies performed between 1999 and 2019 at the university clinic of the Faculty of Dental Medicine of the University of Lisbon was performed, regarding the patient’s gender and age, type of biopsy, location of lesions, clinical and histological diagnosis, and the results were obtained. Association relationships were studied using the chi-square test and the Kruskal-Wallis test to correlate variables. P<0.05 was considered statistically significant. RESULTS: From a total sample of 1448 patients, 826 (57.1%) were female, 610 (42.1%) were male, and 12 (0.8%) had no gender information, with a mean age of 50.14 years (standard deviation ± 17.61). The preferred location was the buccal mucosa, vestibule fundus and alveolar mucosa (20.7%). Benign lesions (BL) were the most common, in 82,8% of the cases, followed by oral potentially malignant disorders (OPMD) in 15,5%, and finally, malignant lesions (ML) in 1.7%. Focal fibrous hyperplasia was the most frequent diagnosis in the total sample (25.6%). In the young group, the most common entity was mucocele (34.0%), with a predominance of the lower lip (32.9%). In OPMD, leukoplakia was the most frequently diagnosed (48,7%). The most common ML was squamous cell carcinoma (92.0%), appearing mainly in the tongue (34.8%). A statistically significant relation between ML and older age was found. CONCLUSIONS: This study included biopsies analysed over a period of 20 years, being BL the main pathology to affect the oral cavity. Although less frequent, OPMD and ML should not be neglected and must be correctly diagnosed and treated. Key words:Oral biopsies, Oral and maxillofacial pathology, Oral medicine, Clinicopathological analysis, Epidemiological study, University clinic.
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spelling pubmed-97999962023-01-03 Oral biopsies in a Portuguese population: A 20-year clinicopathological study in a university clinic de Almeida, Cláudia G. Freitas, Filipe Francisco, Helena Marques, João A. Caramês, João J Clin Exp Dent Research BACKGROUND: Performing a biopsy is very important in oral medicine and the anatomopathological examination is fundamental to obtain or to confirm the diagnosis in oral and maxillofacial pathology. The purpose of this study is to analyse the frequency and characteristic patterns of biopsied oromaxillofacial lesions in a Portuguese population. MATERIAL AND METHODS: A descriptive statistical analysis of the data from the anatomopathological reports of the biopsies performed between 1999 and 2019 at the university clinic of the Faculty of Dental Medicine of the University of Lisbon was performed, regarding the patient’s gender and age, type of biopsy, location of lesions, clinical and histological diagnosis, and the results were obtained. Association relationships were studied using the chi-square test and the Kruskal-Wallis test to correlate variables. P<0.05 was considered statistically significant. RESULTS: From a total sample of 1448 patients, 826 (57.1%) were female, 610 (42.1%) were male, and 12 (0.8%) had no gender information, with a mean age of 50.14 years (standard deviation ± 17.61). The preferred location was the buccal mucosa, vestibule fundus and alveolar mucosa (20.7%). Benign lesions (BL) were the most common, in 82,8% of the cases, followed by oral potentially malignant disorders (OPMD) in 15,5%, and finally, malignant lesions (ML) in 1.7%. Focal fibrous hyperplasia was the most frequent diagnosis in the total sample (25.6%). In the young group, the most common entity was mucocele (34.0%), with a predominance of the lower lip (32.9%). In OPMD, leukoplakia was the most frequently diagnosed (48,7%). The most common ML was squamous cell carcinoma (92.0%), appearing mainly in the tongue (34.8%). A statistically significant relation between ML and older age was found. CONCLUSIONS: This study included biopsies analysed over a period of 20 years, being BL the main pathology to affect the oral cavity. Although less frequent, OPMD and ML should not be neglected and must be correctly diagnosed and treated. Key words:Oral biopsies, Oral and maxillofacial pathology, Oral medicine, Clinicopathological analysis, Epidemiological study, University clinic. Medicina Oral S.L. 2022-12-01 /pmc/articles/PMC9799996/ /pubmed/36601247 http://dx.doi.org/10.4317/jced.59688 Text en Copyright: © 2022 Medicina Oral S.L. https://creativecommons.org/licenses/by/2.5/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
de Almeida, Cláudia G.
Freitas, Filipe
Francisco, Helena
Marques, João A.
Caramês, João
Oral biopsies in a Portuguese population: A 20-year clinicopathological study in a university clinic
title Oral biopsies in a Portuguese population: A 20-year clinicopathological study in a university clinic
title_full Oral biopsies in a Portuguese population: A 20-year clinicopathological study in a university clinic
title_fullStr Oral biopsies in a Portuguese population: A 20-year clinicopathological study in a university clinic
title_full_unstemmed Oral biopsies in a Portuguese population: A 20-year clinicopathological study in a university clinic
title_short Oral biopsies in a Portuguese population: A 20-year clinicopathological study in a university clinic
title_sort oral biopsies in a portuguese population: a 20-year clinicopathological study in a university clinic
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799996/
https://www.ncbi.nlm.nih.gov/pubmed/36601247
http://dx.doi.org/10.4317/jced.59688
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