Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of upper and lower motor neurons, leading to progressive weakness of voluntary muscles, with death following from neuromuscular respiratory failure, typically within 3 to 5 years. There is a stro...

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Autores principales: Al Khleifat, Ahmad, Iacoangeli, Alfredo, Jones, Ashley R., van Vugt, Joke J. F. A., Moisse, Matthieu, Shatunov, Aleksey, Zwamborn, Ramona A. J., van der Spek, Rick A. A., Cooper-Knock, Johnathan, Topp, Simon, van Rheenen, Wouter, Kenna, Brendan, Van Eijk, Kristel R., Kenna, Kevin, Byrne, Ross, López, Victoria, Opie-Martin, Sarah, Vural, Atay, Campos, Yolanda, Weber, Markus, Smith, Bradley, Fogh, Isabella, Silani, Vincenzo, Morrison, Karen E., Dobson, Richard, van Es, Michael A., McLaughlin, Russell L., Vourc’h, Patrick, Chio, Adriano, Corcia, Philippe, de Carvalho, Mamede, Gotkine, Marc, Panades, Monica Povedano, Mora, Jesus S., Shaw, Pamela J., Landers, John E., Glass, Jonathan D., Shaw, Christopher E., Basak, Nazli, Hardiman, Orla, Robberecht, Wim, Van Damme, Philip, van den Berg, Leonard H., Veldink, Jan H., Al-Chalabi, Ammar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799999/
https://www.ncbi.nlm.nih.gov/pubmed/36589292
http://dx.doi.org/10.3389/fncel.2022.1050596

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