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PD-1 Checkpoint Blockade in Patients for Acute Myeloid Leukemia after HSCT Relapse Resulted in Severe GVHD and sHLH

Treatment with immune checkpoint inhibitors (ICI) such as carrizumab leads to immune-mediated adverse effects including severe acute graft versus host disease (aGVHD) and secondary hemophagocytic syndrome (sHLH). Herein, we present two cases where aGVHD and sHLH developed after ICI administration, w...

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Detalles Bibliográficos
Autores principales: Du, Zhi zhuo, Zhou, Mi, Ling, Jing, Cao, Lan, Kong, Lingjun, Cheng, Shengqin, Xiao, Peifang, Hu, Shaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800091/
https://www.ncbi.nlm.nih.gov/pubmed/36590870
http://dx.doi.org/10.1155/2022/1705905

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