Cargando…

A clinical evaluation of gelastic and dacrystic seizures: a multicenter study

Background  Gelastic seizures are extremely rare, short-lasting, unprovoked, and uncontrollable laughing attacks. We conducted this retrospective evaluation to determine whether these symptoms, manifesting in different forms, such as cheerful laughter, laughing, smiling, and sobbing had any value in...

Descripción completa

Detalles Bibliográficos
Autores principales: Demir, Aylin Bican, Öz, Başak Yılmaz, Yıldız, Mustafa Onur, Türk, Bengi Gül, Tanrıverdi, Taner, Bekar, Ahmet, Yeni, Naz, Bora, İbrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800159/
https://www.ncbi.nlm.nih.gov/pubmed/36580957
http://dx.doi.org/10.1055/s-0042-1758755
_version_ 1784861230961262592
author Demir, Aylin Bican
Öz, Başak Yılmaz
Yıldız, Mustafa Onur
Türk, Bengi Gül
Tanrıverdi, Taner
Bekar, Ahmet
Yeni, Naz
Bora, İbrahim
author_facet Demir, Aylin Bican
Öz, Başak Yılmaz
Yıldız, Mustafa Onur
Türk, Bengi Gül
Tanrıverdi, Taner
Bekar, Ahmet
Yeni, Naz
Bora, İbrahim
author_sort Demir, Aylin Bican
collection PubMed
description Background  Gelastic seizures are extremely rare, short-lasting, unprovoked, and uncontrollable laughing attacks. We conducted this retrospective evaluation to determine whether these symptoms, manifesting in different forms, such as cheerful laughter, laughing, smiling, and sobbing had any value in terms of etiology or localization. Methods  A total of 31 patients who exhibited bouts of laughing or crying and who were under follow-up between 2000 and 2019 at tertiary epilepsy centers were included in the study. Laughing seizures were divided into three groups in terms of semiology (i.e., laughter with mirth, laughter without mirth, and smile). Dacrystic seizures were accompanied by some gelastic seizures and were divided into two groups in terms of semiology (i.e., weeping loudly [motor and voice-sobbing] and crying). Results  Of the 27 patients with laughing seizures, 12 had seizures that manifested with smiling, 7 had seizures that manifested with laughing and mirth, and 8 had seizures that manifested with laughter without mirth. Dacrystic-gelastic seizures were observed in four patients, among whom 2 patients had crying and laughter without mirth and 2 patients had weeping loudly and laughter without mirth episodes. Conclusion  Gelastic and dacrystic seizures often suggest hypothalamic hamartomas, in the literature. This rare ictal behavior can originate from different cortical locations and lesions of a different nature. However, we found that gelastic seizures with smiling were a more homogenous group with regard to location in the temporal lobe, which we aimed to show by evaluating the patients included in this study.
format Online
Article
Text
id pubmed-9800159
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Thieme Revinter Publicações Ltda.
record_format MEDLINE/PubMed
spelling pubmed-98001592023-01-09 A clinical evaluation of gelastic and dacrystic seizures: a multicenter study Demir, Aylin Bican Öz, Başak Yılmaz Yıldız, Mustafa Onur Türk, Bengi Gül Tanrıverdi, Taner Bekar, Ahmet Yeni, Naz Bora, İbrahim Arq Neuropsiquiatr Background  Gelastic seizures are extremely rare, short-lasting, unprovoked, and uncontrollable laughing attacks. We conducted this retrospective evaluation to determine whether these symptoms, manifesting in different forms, such as cheerful laughter, laughing, smiling, and sobbing had any value in terms of etiology or localization. Methods  A total of 31 patients who exhibited bouts of laughing or crying and who were under follow-up between 2000 and 2019 at tertiary epilepsy centers were included in the study. Laughing seizures were divided into three groups in terms of semiology (i.e., laughter with mirth, laughter without mirth, and smile). Dacrystic seizures were accompanied by some gelastic seizures and were divided into two groups in terms of semiology (i.e., weeping loudly [motor and voice-sobbing] and crying). Results  Of the 27 patients with laughing seizures, 12 had seizures that manifested with smiling, 7 had seizures that manifested with laughing and mirth, and 8 had seizures that manifested with laughter without mirth. Dacrystic-gelastic seizures were observed in four patients, among whom 2 patients had crying and laughter without mirth and 2 patients had weeping loudly and laughter without mirth episodes. Conclusion  Gelastic and dacrystic seizures often suggest hypothalamic hamartomas, in the literature. This rare ictal behavior can originate from different cortical locations and lesions of a different nature. However, we found that gelastic seizures with smiling were a more homogenous group with regard to location in the temporal lobe, which we aimed to show by evaluating the patients included in this study. Thieme Revinter Publicações Ltda. 2022-12-29 /pmc/articles/PMC9800159/ /pubmed/36580957 http://dx.doi.org/10.1055/s-0042-1758755 Text en Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Demir, Aylin Bican
Öz, Başak Yılmaz
Yıldız, Mustafa Onur
Türk, Bengi Gül
Tanrıverdi, Taner
Bekar, Ahmet
Yeni, Naz
Bora, İbrahim
A clinical evaluation of gelastic and dacrystic seizures: a multicenter study
title A clinical evaluation of gelastic and dacrystic seizures: a multicenter study
title_full A clinical evaluation of gelastic and dacrystic seizures: a multicenter study
title_fullStr A clinical evaluation of gelastic and dacrystic seizures: a multicenter study
title_full_unstemmed A clinical evaluation of gelastic and dacrystic seizures: a multicenter study
title_short A clinical evaluation of gelastic and dacrystic seizures: a multicenter study
title_sort clinical evaluation of gelastic and dacrystic seizures: a multicenter study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800159/
https://www.ncbi.nlm.nih.gov/pubmed/36580957
http://dx.doi.org/10.1055/s-0042-1758755
work_keys_str_mv AT demiraylinbican aclinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT ozbasakyılmaz aclinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT yıldızmustafaonur aclinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT turkbengigul aclinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT tanrıverditaner aclinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT bekarahmet aclinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT yeninaz aclinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT boraibrahim aclinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT demiraylinbican clinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT ozbasakyılmaz clinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT yıldızmustafaonur clinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT turkbengigul clinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT tanrıverditaner clinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT bekarahmet clinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT yeninaz clinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy
AT boraibrahim clinicalevaluationofgelasticanddacrysticseizuresamulticenterstudy