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Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery (MINDDS): A single-centre, parallel-arm, randomised, placebo-controlled superiority trial

BACKGROUND: The delirium-sparing effect of nighttime dexmedetomidine has not been studied after surgery. We hypothesised that a nighttime dose of dexmedetomidine would reduce the incidence of postoperative delirium as compared to placebo. METHODS: This single-centre, parallel-arm, randomised, placeb...

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Detalles Bibliográficos
Autores principales: Qu, Jason Z., Mueller, Ariel, McKay, Tina B., Westover, M. Brandon, Shelton, Kenneth T., Shaefi, Shahzad, D'Alessandro, David A., Berra, Lorenzo, Brown, Emery N., Houle, Timothy T., Akeju, Oluwaseun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800196/
https://www.ncbi.nlm.nih.gov/pubmed/36590787
http://dx.doi.org/10.1016/j.eclinm.2022.101796

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