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A PDX model combined with CD-DST assay to evaluate the antitumor properties of KRpep-2d and oxaliplatin in KRAS (G12D) mutant colorectal cancer

Patient-derived xenograft (PDX) models are more faithful in maintaining the characteristics of human tumors than cell lines and are widely used in drug development, although they have some disadvantages, including their relative low success rate, long turn-around time, and high costs. The collagen g...

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Detalles Bibliográficos
Autores principales: Li, Wuguo, Chen, Wei, Wang, Jialin, Zhao, Guangyin, Chen, Lianzhou, Wan, Yong, Luo, Qianxin, Li, Wenwen, Huang, Haoji, Li, Wenying, Li, Wu, Yang, Yutong, Chen, Daici, Su, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800201/
https://www.ncbi.nlm.nih.gov/pubmed/36590511
http://dx.doi.org/10.1016/j.heliyon.2022.e12518

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