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CDR1as regulates α-synuclein-mediated ischemic brain damage by controlling miR-7 availability

Transient focal ischemia decreased microRNA-7 (miR-7) levels, leading to derepression of its major target α-synuclein (α-Syn) that promotes secondary brain damage. Circular RNA CDR1as is known to regulate miR-7 abundance and function. Hence, we currently evaluated its functional significance after f...

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Detalles Bibliográficos
Autores principales:	Mehta, Suresh L., Chokkalla, Anil K., Bathula, Saivenkateshkomal, Arruri, Vijay, Chelluboina, Bharath, Vemuganti, Raghu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800254/ https://www.ncbi.nlm.nih.gov/pubmed/36618263 http://dx.doi.org/10.1016/j.omtn.2022.11.022

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