Transcriptomic analysis of the innate immune response to in vitro transfection of plasmid DNA

The innate immune response to cytosolic DNA is intended to protect the host from viral infections, but it can also inhibit the delivery and expression of therapeutic transgenes in gene and cell therapies. The goal of this work was to use mRNA sequencing to identify genes that may influence transfect...

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Detalles Bibliográficos
Autores principales: Warga, Eric, Anderson, Jared, Tucker, Matthew, Harris, Emily, Elmer, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800263/
https://www.ncbi.nlm.nih.gov/pubmed/36618265
http://dx.doi.org/10.1016/j.omtn.2022.11.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800263/
https://www.ncbi.nlm.nih.gov/pubmed/36618265
http://dx.doi.org/10.1016/j.omtn.2022.11.025

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