A peptide derived from adaptor protein STAP-2 inhibits tumor progression by downregulating epidermal growth factor receptor signaling

Signal-transducing adaptor family member-2 (STAP-2) is an adaptor protein that regulates various intracellular signals. We previously demonstrated that STAP-2 binds to epidermal growth factor receptor (EGFR) and facilitates its stability and activation of EGFR signaling in prostate cancer cells. Inh...

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Detalles Bibliográficos
Autores principales: Maemoto, Taiga, Kitai, Yuichi, Takahashi, Runa, Shoji, Haruka, Yamada, Shunsuke, Takei, Shiho, Ito, Daiki, Muromoto, Ryuta, Kashiwakura, Jun-ichi, Handa, Haruka, Hashimoto, Ari, Hashimoto, Shigeru, Ose, Toyoyuki, Oritani, Kenji, Matsuda, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800302/
https://www.ncbi.nlm.nih.gov/pubmed/36410436
http://dx.doi.org/10.1016/j.jbc.2022.102724

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