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Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

MR1-restricted T (MR1T) cells recognize microbial small molecule metabolites presented on the MHC Class I-like molecule MR1 and have been implicated in early effector responses to microbial infection. As a result, there is considerable interest in identifying chemical properties of metabolite ligand...

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Detalles Bibliográficos
Autores principales:	Jin, Haihong, Ladd, Nicole A., Peev, Andrew M., Swarbrick, Gwendolyn M., Cansler, Meghan, Null, Megan, Boughter, Christopher T., McMurtrey, Curtis, Nilsen, Aaron, Dobos, Karen M., Hildebrand, William H., Lewinsohn, Deborah A., Adams, Erin J., Lewinsohn, David M., Harriff, Melanie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800373/ https://www.ncbi.nlm.nih.gov/pubmed/36581641 http://dx.doi.org/10.1038/s41598-022-26259-y

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