Transcriptome analysis of a dog model of congestive heart failure shows that collagen-related 2-oxoglutarate-dependent dioxygenases contribute to heart failure

Fibrosis is an important pathological mechanism in heart failure (HF) and is associated with poor prognosis. We analyzed fibrosis in HF patients using transcriptomic data. Genes differentially expressed between normal control and congestive HF (CHF) dogs included P3H1, P3H2, P3H4, P4HA2, PLOD1 and P...

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Detalles Bibliográficos
Autores principales: Isono, Takahiro, Matsumoto, Takehiro, Suzaki, Masafumi, Kubota, Shigehisa, Kageyama, Susumu, Kawauchi, Akihiro, Wada, Atuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800379/
https://www.ncbi.nlm.nih.gov/pubmed/36581661
http://dx.doi.org/10.1038/s41598-022-26717-7

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