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The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs
The spread of Coronavirus Disease 2019 (COVID-19) has already reached a pandemic dimension within a few weeks. Italy has been one of the first countries dealing with the outbreak of COVID-19, and severe measures have been adopted to limit viral transmission. The spread of COVID-19 may have several i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800493/ https://www.ncbi.nlm.nih.gov/pubmed/32243677 http://dx.doi.org/10.1111/ajt.15904 |
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author | Angelico, Roberta Trapani, Silvia Manzia, Tommaso Maria Lombardini, Letizia Tisone, Giuseppe Cardillo, Massimo |
author_facet | Angelico, Roberta Trapani, Silvia Manzia, Tommaso Maria Lombardini, Letizia Tisone, Giuseppe Cardillo, Massimo |
author_sort | Angelico, Roberta |
collection | PubMed |
description | The spread of Coronavirus Disease 2019 (COVID-19) has already reached a pandemic dimension within a few weeks. Italy has been one of the first countries dealing with the outbreak of COVID-19, and severe measures have been adopted to limit viral transmission. The spread of COVID-19 may have several implications in organ transplant activity that physicians should be aware of. The initial experience gained during the COVID-19 outbreak shows that around 10% of infected patients in Italy need intensive care management to overcome the acute respiratory distress syndrome. Due to the exponential rise of infected patients we are now facing an actual risk of saturation of intensive care unit (ICU) beds. A restriction in the number of ICU beds available for both donors and transplant recipients may unfavorably influence the overall donation activity, and eventually lead to a reduced number of transplants. Preliminary Italian data show that a 25% reduction of procured organs has already occurred during the first 4 weeks of COVID-19 outbreak. This underlines the need to closely monitor what will be further happening in ICUs due to the COVID-19 spread in the attempt to preserve transplant activity, especially in Western countries where deceased donors represent the major organ resource. |
format | Online Article Text |
id | pubmed-9800493 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98004932022-12-30 The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs Angelico, Roberta Trapani, Silvia Manzia, Tommaso Maria Lombardini, Letizia Tisone, Giuseppe Cardillo, Massimo Am J Transplant Personal Viewpoint The spread of Coronavirus Disease 2019 (COVID-19) has already reached a pandemic dimension within a few weeks. Italy has been one of the first countries dealing with the outbreak of COVID-19, and severe measures have been adopted to limit viral transmission. The spread of COVID-19 may have several implications in organ transplant activity that physicians should be aware of. The initial experience gained during the COVID-19 outbreak shows that around 10% of infected patients in Italy need intensive care management to overcome the acute respiratory distress syndrome. Due to the exponential rise of infected patients we are now facing an actual risk of saturation of intensive care unit (ICU) beds. A restriction in the number of ICU beds available for both donors and transplant recipients may unfavorably influence the overall donation activity, and eventually lead to a reduced number of transplants. Preliminary Italian data show that a 25% reduction of procured organs has already occurred during the first 4 weeks of COVID-19 outbreak. This underlines the need to closely monitor what will be further happening in ICUs due to the COVID-19 spread in the attempt to preserve transplant activity, especially in Western countries where deceased donors represent the major organ resource. American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. 2020-07 2022-12-30 /pmc/articles/PMC9800493/ /pubmed/32243677 http://dx.doi.org/10.1111/ajt.15904 Text en Copyright © 2020 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Personal Viewpoint Angelico, Roberta Trapani, Silvia Manzia, Tommaso Maria Lombardini, Letizia Tisone, Giuseppe Cardillo, Massimo The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs |
title | The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs |
title_full | The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs |
title_fullStr | The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs |
title_full_unstemmed | The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs |
title_short | The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs |
title_sort | covid-19 outbreak in italy: initial implications for organ transplantation programs |
topic | Personal Viewpoint |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800493/ https://www.ncbi.nlm.nih.gov/pubmed/32243677 http://dx.doi.org/10.1111/ajt.15904 |
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