Axl receptor induces efferocytosis, dampens M1 macrophage responses and promotes heart pathology in Trypanosoma cruzi infection

Adaptive immunity controls Trypanosoma cruzi infection, but the protozoan parasite persists and causes Chagas disease. T cells undergo apoptosis, and the efferocytosis of apoptotic cells might suppress macrophages and exacerbate parasite infection. Nonetheless, the receptors involved in the efferocy...

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Detalles Bibliográficos
Autores principales: Rigoni, Thaís S., Vellozo, Natália S., Guimarães-Pinto, Kamila, Cabral-Piccin, Mariela, Fabiano-Coelho, Laryssa, Matos-Silva, Thayane C., Filardy, Alessandra A., Takiya, Christina M., Lopes, Marcela F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800583/
https://www.ncbi.nlm.nih.gov/pubmed/36581764
http://dx.doi.org/10.1038/s42003-022-04401-w

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