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Coal dust nanoparticles induced pulmonary fibrosis by promoting inflammation and epithelial-mesenchymal transition via the NF-κB/NLRP3 pathway driven by IGF1/ROS-mediated AKT/GSK3β signals

Pneumoconiosis is the most common and serious disease among coal miners. In earlier work on this subject, we documented that coal dust (CD) nanoparticles (CD-NPs) induced pulmonary fibrosis (PF) more profoundly than did CD micron particles (CD-MPs), but the mechanism has not been thoroughly studied....

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Detalles Bibliográficos
Autores principales: Zhang, Yinci, Liang, Jiaojiao, Cao, Niandie, Gao, Jiafeng, Song, Li, Tang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800584/
https://www.ncbi.nlm.nih.gov/pubmed/36581638
http://dx.doi.org/10.1038/s41420-022-01291-z