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Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal”

In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation. Our LTx practice during the early pandemic may provide a...

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Autores principales: Halpern, Samantha E., Olaso, Danae G., Krischak, Madison K., Reynolds, John M., Haney, John C., Klapper, Jacob A., Hartwig, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800716/
https://www.ncbi.nlm.nih.gov/pubmed/32894641
http://dx.doi.org/10.1111/ajt.16304
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author Halpern, Samantha E.
Olaso, Danae G.
Krischak, Madison K.
Reynolds, John M.
Haney, John C.
Klapper, Jacob A.
Hartwig, Matthew G.
author_facet Halpern, Samantha E.
Olaso, Danae G.
Krischak, Madison K.
Reynolds, John M.
Haney, John C.
Klapper, Jacob A.
Hartwig, Matthew G.
author_sort Halpern, Samantha E.
collection PubMed
description In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation. Our LTx practice during the early pandemic may provide a blueprint for managing LTx in an era of continued community prevalence. Patients who underwent LTx at our institution between March 1 and May 20, 2020 were included. Recipient, operative, and donor characteristics were compared to those from our program in 2019, and COVID-19 testing practices were evaluated for March, April, and May to understand how our practice adapted to the pandemic. Our program performed 36 LTx, 33% more than the same period in 2019. Recipient, operative, and donor characteristics during COVID-19 were similar to those in 2019. By April 1, all donors and recipients underwent pretransplant COVID-19 testing, all returning negative results. To date, no recipients have developed posttransplant COVID-19. At our institution, pretransplant COVID-19 testing, use of local donor lungs, and avoidance of donors from areas of increased community penetration supported a safe and effective LTx practice during the early COVID-19 pandemic. Continued follow-up is required to ensure the long-term safety of these newly transplanted patients.
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spelling pubmed-98007162022-12-30 Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal” Halpern, Samantha E. Olaso, Danae G. Krischak, Madison K. Reynolds, John M. Haney, John C. Klapper, Jacob A. Hartwig, Matthew G. Am J Transplant Brief Communication In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation. Our LTx practice during the early pandemic may provide a blueprint for managing LTx in an era of continued community prevalence. Patients who underwent LTx at our institution between March 1 and May 20, 2020 were included. Recipient, operative, and donor characteristics were compared to those from our program in 2019, and COVID-19 testing practices were evaluated for March, April, and May to understand how our practice adapted to the pandemic. Our program performed 36 LTx, 33% more than the same period in 2019. Recipient, operative, and donor characteristics during COVID-19 were similar to those in 2019. By April 1, all donors and recipients underwent pretransplant COVID-19 testing, all returning negative results. To date, no recipients have developed posttransplant COVID-19. At our institution, pretransplant COVID-19 testing, use of local donor lungs, and avoidance of donors from areas of increased community penetration supported a safe and effective LTx practice during the early COVID-19 pandemic. Continued follow-up is required to ensure the long-term safety of these newly transplanted patients. American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. 2020-11 2022-12-30 /pmc/articles/PMC9800716/ /pubmed/32894641 http://dx.doi.org/10.1111/ajt.16304 Text en Copyright © 2020 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Communication
Halpern, Samantha E.
Olaso, Danae G.
Krischak, Madison K.
Reynolds, John M.
Haney, John C.
Klapper, Jacob A.
Hartwig, Matthew G.
Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal”
title Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal”
title_full Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal”
title_fullStr Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal”
title_full_unstemmed Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal”
title_short Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal”
title_sort lung transplantation during the covid-19 pandemic: safely navigating the new “normal”
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800716/
https://www.ncbi.nlm.nih.gov/pubmed/32894641
http://dx.doi.org/10.1111/ajt.16304
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