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Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal”
In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation. Our LTx practice during the early pandemic may provide a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800716/ https://www.ncbi.nlm.nih.gov/pubmed/32894641 http://dx.doi.org/10.1111/ajt.16304 |
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author | Halpern, Samantha E. Olaso, Danae G. Krischak, Madison K. Reynolds, John M. Haney, John C. Klapper, Jacob A. Hartwig, Matthew G. |
author_facet | Halpern, Samantha E. Olaso, Danae G. Krischak, Madison K. Reynolds, John M. Haney, John C. Klapper, Jacob A. Hartwig, Matthew G. |
author_sort | Halpern, Samantha E. |
collection | PubMed |
description | In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation. Our LTx practice during the early pandemic may provide a blueprint for managing LTx in an era of continued community prevalence. Patients who underwent LTx at our institution between March 1 and May 20, 2020 were included. Recipient, operative, and donor characteristics were compared to those from our program in 2019, and COVID-19 testing practices were evaluated for March, April, and May to understand how our practice adapted to the pandemic. Our program performed 36 LTx, 33% more than the same period in 2019. Recipient, operative, and donor characteristics during COVID-19 were similar to those in 2019. By April 1, all donors and recipients underwent pretransplant COVID-19 testing, all returning negative results. To date, no recipients have developed posttransplant COVID-19. At our institution, pretransplant COVID-19 testing, use of local donor lungs, and avoidance of donors from areas of increased community penetration supported a safe and effective LTx practice during the early COVID-19 pandemic. Continued follow-up is required to ensure the long-term safety of these newly transplanted patients. |
format | Online Article Text |
id | pubmed-9800716 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98007162022-12-30 Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal” Halpern, Samantha E. Olaso, Danae G. Krischak, Madison K. Reynolds, John M. Haney, John C. Klapper, Jacob A. Hartwig, Matthew G. Am J Transplant Brief Communication In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation. Our LTx practice during the early pandemic may provide a blueprint for managing LTx in an era of continued community prevalence. Patients who underwent LTx at our institution between March 1 and May 20, 2020 were included. Recipient, operative, and donor characteristics were compared to those from our program in 2019, and COVID-19 testing practices were evaluated for March, April, and May to understand how our practice adapted to the pandemic. Our program performed 36 LTx, 33% more than the same period in 2019. Recipient, operative, and donor characteristics during COVID-19 were similar to those in 2019. By April 1, all donors and recipients underwent pretransplant COVID-19 testing, all returning negative results. To date, no recipients have developed posttransplant COVID-19. At our institution, pretransplant COVID-19 testing, use of local donor lungs, and avoidance of donors from areas of increased community penetration supported a safe and effective LTx practice during the early COVID-19 pandemic. Continued follow-up is required to ensure the long-term safety of these newly transplanted patients. American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. 2020-11 2022-12-30 /pmc/articles/PMC9800716/ /pubmed/32894641 http://dx.doi.org/10.1111/ajt.16304 Text en Copyright © 2020 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Brief Communication Halpern, Samantha E. Olaso, Danae G. Krischak, Madison K. Reynolds, John M. Haney, John C. Klapper, Jacob A. Hartwig, Matthew G. Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal” |
title | Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal” |
title_full | Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal” |
title_fullStr | Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal” |
title_full_unstemmed | Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal” |
title_short | Lung transplantation during the COVID-19 pandemic: Safely navigating the new “normal” |
title_sort | lung transplantation during the covid-19 pandemic: safely navigating the new “normal” |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800716/ https://www.ncbi.nlm.nih.gov/pubmed/32894641 http://dx.doi.org/10.1111/ajt.16304 |
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