BAG2 drives chemoresistance of breast cancer by exacerbating mutant p53 aggregate

Rationale: Chemoresistance is a major challenge in the clinical management of patients with breast cancer. Mutant p53 proteins tend to form aggregates that promote tumorigenesis in cancers. We here aimed to explore the mechanism for the generation of mutant p53 aggregates in breast cancer and assess...

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Detalles Bibliográficos
Autores principales: Huang, Xinjian, Shi, Dongni, Zou, Xuxiazi, Wu, Xuxia, Huang, Shumei, Kong, Lingzhi, Yang, Muwen, Xiao, Yunyun, Chen, Boyu, Chen, Xiangfu, Ouyang, Ying, Song, Libing, Jian, Yunting, Lin, Chuyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800719/
https://www.ncbi.nlm.nih.gov/pubmed/36593950
http://dx.doi.org/10.7150/thno.78492

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