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Artificial intelligence-based recognition for variant pathogenicity of BRCA1 using AlphaFold2-predicted structures
With the surge of the high-throughput sequencing technologies, many genetic variants have been identified in the past decade. The vast majority of these variants are defined as variants of uncertain significance (VUS), as their significance to the function or health of an organism is not known. It i...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800725/ https://www.ncbi.nlm.nih.gov/pubmed/36593954 http://dx.doi.org/10.7150/thno.79362 |