Cargando…

De novo transcriptome assembly and functional analysis reveal a dihydrochalcone 3-hydroxylase(DHC3H) of wild Malus species that produces sieboldin in vivo

Sieboldin is a specialised secondary metabolite of the group of dihydrochalcones (DHC), found in high concentrations only in some wild Malus species, closely related to the domesticated apple (Malus × domestica L.). To date, the first committed step towards the biosynthesis of sieboldin remains unkn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miranda, Simón, Lagrèze, Jorge, Knoll, Anne-Sophie, Angeli, Andrea, Espley, Richard V., Dare, Andrew P., Malnoy, Mickael, Martens, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Plant Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800874/ https://www.ncbi.nlm.nih.gov/pubmed/36589107 http://dx.doi.org/10.3389/fpls.2022.1072765

Ejemplares similares

Chasing Consistency: An Update of the TCP Gene Family of Malus × Domestica
por: Tabarelli, Mattia, et al.
Publicado: (2022)

Molecular and Enzymatic Characterization of Flavonoid 3′-Hydroxylase of Malus × domestica
por: Weissensteiner, Julia, et al.
Publicado: (2021)

The DHC1b (DHC2) Isoform of Cytoplasmic Dynein Is Required for Flagellar Assembly
por: Pazour, Gregory J., et al.
Publicado: (1999)

The knock‐down of the expression of MdMLO19 reduces susceptibility to powdery mildew (Podosphaera leucotricha) in apple (Malus domestica)
por: Pessina, Stefano, et al.
Publicado: (2016)

Molecular characterization of intergeneric hybrids between Malus and Pyrus
por: Pasqualetto, Giulia, et al.
Publicado: (2022)

Metabolic engineering of Saccharomyces cerevisiae for de novo production of dihydrochalcones with known antioxidant, antidiabetic, and sweet tasting properties
por: Eichenberger, Michael, et al.
Publicado: (2017)

Characterization of the MLO gene family in Rosaceae and gene expression analysis in Malus domestica
por: Pessina, Stefano, et al.
Publicado: (2014)

Transcriptional regulation of MdmiR285N microRNA in apple (Malus x domestica) and the heterologous plant system Arabidopsis thaliana
por: Pompili, Valerio, et al.
Publicado: (2020)

Dihydrochalcone glycosides from Oxytropis myriophylla
por: She, Gaimei, et al.
Publicado: (2011)

Genetic Analysis and Fine Mapping of the Fire Blight Resistance Locus of Malus ×arnoldiana on Linkage Group 12 Reveal First Candidate Genes
por: Emeriewen, Ofere Francis, et al.
Publicado: (2021)

Characterization of Resistance Gene Analogues (RGAs) in Apple (Malus × domestica Borkh.) and Their Evolutionary History of the Rosaceae Family
por: Perazzolli, Michele, et al.
Publicado: (2014)

Identification of genes differentially expressed during interaction of resistant and susceptible apple cultivars (Malus × domestica) with Erwinia amylovora
por: Baldo, Angela, et al.
Publicado: (2010)

Neohesperidin Dihydrochalcone and Neohesperidin Dihydrochalcone-O-Glycoside Attenuate Subcutaneous Fat and Lipid Accumulation by Regulating PI3K/AKT/mTOR Pathway In Vivo and In Vitro
por: Kwon, Minseo, et al.
Publicado: (2022)

Neuroprotective Effects of Early Hypothermia Induced by Phenothiazines and DHC in Ischemic Stroke
por: Han, Yun, et al.
Publicado: (2021)

Dihydrochalcones and Diterpenoids from Pteris ensiformis and Their Bioactivities
por: Shi, Yu-Sheng, et al.
Publicado: (2017)

Candidate gene mapping identifies genomic variations in the fire blight susceptibility genes HIPM and DIPM across the Malus germplasm
por: Tegtmeier, Richard, et al.
Publicado: (2020)

Synthesis and study the analgesic and anti-inflammatory effects of rigid benzofurane 3, 4 dihydroxy chalcon (DHC) in mice
por: Heidari, Mahmoud Reza, et al.
Publicado: (2010)

Author Correction: Candidate gene mapping identifies genomic variations in the fire blight susceptibility genes HIPM and DIPM across the Malus germplasm
por: Tegtmeier, Richard, et al.
Publicado: (2021)

Construction of a dense genetic map of the Malus fusca fire blight resistant accession MAL0045 using tunable genotyping-by-sequencing SNPs and microsatellites
por: Emeriewen, Ofere Francis, et al.
Publicado: (2020)

Antioxidant Structure–Activity Relationship Analysis of Five Dihydrochalcones
por: Li, Xican, et al.
Publicado: (2018)

The Bioavailability, Extraction, Biosynthesis and Distribution of Natural Dihydrochalcone: Phloridzin
por: Tian, Lei, et al.
Publicado: (2021)

Dihydrochalcones in Sweet Tea: Biosynthesis, Distribution and Neuroprotection Function
por: Wang, Yong-Kang, et al.
Publicado: (2022)

Frequency of a natural truncated allele of MdMLO19 in the germplasm of Malus domestica
por: Pessina, Stefano, et al.
Publicado: (2017)

Phenotypic divergence between the cultivated apple (Malus domestica) and its primary wild progenitor (Malus sieversii)
por: Davies, Thomas, et al.
Publicado: (2022)

Regulators of the Actin Cytoskeleton Mediate Lethality in a Caenorhabditis elegans dhc-1 Mutant
por: Gil-Krzewska, Aleksandra J., et al.
Publicado: (2010)

The medaka dhc2 mutant reveals conserved and distinct mechanisms of Hedgehog signaling in teleosts
por: Yamamoto, Takayoshi, et al.
Publicado: (2015)

Differential expression of CPKs and cytosolic Ca(2+) variation in resistant and susceptible apple cultivars (Malus x domestica) in response to the pathogen Erwinia amylovora and mechanical wounding
por: Kanchiswamy, Chidananda Nagamangala, et al.
Publicado: (2013)

The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor
por: Winnig, Marcel, et al.
Publicado: (2007)

Development of dihydrochalcone-functionalized gold nanoparticles for augmented antineoplastic activity
por: Payne, Jason N, et al.
Publicado: (2018)

Dihydrochalcones with Antiinflammatory Activity from Leaves and Twigs of Cyathostemma argenteum
por: Somsrisa, Jariya, et al.
Publicado: (2013)

Isolation of Monoterpene Dihydrochalcones from Piper montealegreanum Yuncker (Piperaceae)
por: Alves, Harley da Silva, et al.
Publicado: (2017)

Intestinal Transport Characteristics and Metabolism of C-Glucosyl Dihydrochalcone, Aspalathin
por: Bowles, Sandra, et al.
Publicado: (2017)

De novo biosynthesis of garbanzol and fustin in Streptomyces albus based on a potential flavanone 3‐hydroxylase with 2‐hydroxylase side activity
por: Marín, Laura, et al.
Publicado: (2021)

Discovery of Dihydrochalcone as Potential Lead for Alzheimer’s Disease: In Silico and In Vitro Study
por: Viet, Man Hoang, et al.
Publicado: (2013)

Biochemical Basis of Anti-Cancer-Effects of Phloretin—A Natural Dihydrochalcone
por: Choi, Bu Young
Publicado: (2019)

Chalcones and Dihydrochalcones Augment TRAIL-Mediated Apoptosis in Prostate Cancer Cells
por: Szliszka, Ewelina, et al.
Publicado: (2010)

Dihydrochalcone Derivatives from Populus balsamifera L. Buds for the Treatment of Psoriasis
por: Bélanger, Audrey, et al.
Publicado: (2019)

Dihydrochalcones: Methods of Acquisition and Pharmacological Properties—A First Systematic Review
por: Stompor, Monika, et al.
Publicado: (2019)

Re‐evaluation of neohesperidine dihydrochalcone (E 959) as a food additive
por: Younes, Maged, et al.
Publicado: (2022)

Domain Hierarchy and closed Loops (DHcL): a server for exploring hierarchy of protein domain structure
por: Koczyk, Grzegorz, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_gb42g2gmme935nonthfj61ol15