Cargando…

A proof-of-concept study poised to remodel the drug development process: Liver-Chip solutions for lead optimization and predictive toxicology

Detalles Bibliográficos
Autor principal:	Nahle, Zaher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medical Technology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800902/ https://www.ncbi.nlm.nih.gov/pubmed/36590153 http://dx.doi.org/10.3389/fmedt.2022.1053588

Ejemplares similares

Proof-of-concept study of compartmentalized lung ventilation using system for asymmetric flow regulation (SAFR)
por: Barjaktarevic, Igor, et al.
Publicado: (2023)

Multiple Sclerosis: LIFNano-CD4 for Trojan Horse Delivery of the Neuro-Protective Biologic “LIF” Into the Brain: Preclinical Proof of Concept
por: de la Flor, Raul, et al.
Publicado: (2021)

A Novel Laser Energy Ablation Catheter for Endocardial Cavo-Tricuspid Isthmus Ablation and Epicardial Ventricular Lesion Formation: An in vivo Proof-of-Concept Study
por: Krist, Dennis, et al.
Publicado: (2022)

Critical Study on the Tube-to-Chip Luer Slip Connectors
por: Etxeberria, Leire, et al.
Publicado: (2022)

Embracing Mechanobiology in Next Generation Organ-On-A-Chip Models of Bone Metastasis
por: Slay, Ellen E., et al.
Publicado: (2021)

An eye-tracking based robotic scrub nurse: proof of concept
por: Ezzat, Ahmed, et al.
Publicado: (2021)

Robust Formation of an Epithelial Layer of Human Intestinal Organoids in a Polydimethylsiloxane-Based Gut-on-a-Chip Microdevice
por: Shin, Woojung, et al.
Publicado: (2020)

Hydro-jet propelled colonoscopy: proof of concept in a phantom colon
por: Coleman, Stuart A., et al.
Publicado: (2020)

Mechanical Cardiac Support With an Implantable Direct Cardiac Compression Device: Proof of Concept
por: Letsou, George V., et al.
Publicado: (2022)

Medical Device Sterilization and Reprocessing in the Era of Multidrug-Resistant (MDR) Bacteria: Issues and Regulatory Concepts
por: Josephs-Spaulding, Jonathan, et al.
Publicado: (2021)

Research and development of the sOLVe Tube™ dual lumen endobronchial tube: from concept to construct
por: Nwajuaku, Patricia, et al.
Publicado: (2023)

Access and reimbursement pathways for digital health solutions and in vitro diagnostic devices: Current scenario and challenges
por: Mantovani, Andrea, et al.
Publicado: (2023)

Application of in silico Platform for the Development and Optimization of Fully Bioresorbable Vascular Scaffold Designs
por: Milosevic, Miljan, et al.
Publicado: (2021)

Measuring Differential Volume Using the Subtraction Tool for Three-Dimensional Breast Volumetry: A Proof of Concept Study
por: Jeon, Faith Hyun Kyung, et al.
Publicado: (2020)

Optimization of Anti-SARS-CoV-2 Neutralizing Antibody Therapies: Roadmap to Improve Clinical Effectiveness and Implementation
por: van der Straten, Karlijn, et al.
Publicado: (2022)

Effectiveness of REAC neuro postural and neuro psycho physical optimization in improving peripheral vasospasm dysfunction: a case report
por: Bechelli, Fabio
Publicado: (2023)

Changing liver utilization and discard rates in clinical transplantation in the ex-vivo machine preservation era
por: Azizieh, Yara, et al.
Publicado: (2023)

Can Electric Nose Breath Analysis Identify Abdominal Wall Hernia Recurrence and Aortic Aneurysms? A Proof-of-Concept Study
por: Mommers, Elwin H. H., et al.
Publicado: (2020)

Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury
por: Cox, Christopher R., et al.
Publicado: (2020)

Poised to migrate
por: Wells, William A.
Publicado: (2003)

The Poise of Scholarship
por: Hopkins, Henry Reed
Publicado: (1909)

The Place and Importance of Patients in Deliberative Processes
por: Cellier, Marjo S.
Publicado: (2021)

Patient Involvement in the Health Technology Assessment Process in Taiwan
por: Chen, Kuei An, et al.
Publicado: (2022)

Systems and processes for regulation of investigational medical devices in Uganda
por: Mpaata, Charles Norman, et al.
Publicado: (2023)

Modeling the Three-Dimensional Bioprinting Process of β-Sheet Self-Assembling Peptide Hydrogel Scaffolds
por: Chiesa, Irene, et al.
Publicado: (2020)

A case study: Re-evaluating the biological risk following a processing aid change on a marketed cardiovascular implant device
por: Hsia, Frances K., et al.
Publicado: (2022)

Predictive overfitting in immunological applications: Pitfalls and solutions
por: Gygi, Jeremy P., et al.
Publicado: (2023)

Creation of a Proof-of-Concept 3D-Printed Spinal Lateral Access Simulator
por: Pullen, Michael W, et al.
Publicado: (2022)

The Foulage Test: Proof of Concept of a Novel Stepping Test Using a Stabilometer
por: Miwa, Toru, et al.
Publicado: (2022)

The expression of pregnancy-associated plasma protein-A (PAPP-A) in human blastocoel fluid–conditioned media: a proof of concept study
por: Kavoussi, Shahryar K., et al.
Publicado: (2022)

Non-invasive wearables for remote monitoring of HbA1c and glucose variability: proof of concept
por: Bent, Brinnae, et al.
Publicado: (2021)

Single-port robotic transcervical long-segment thoracic tracheal reconstruction: Cadaveric proof-of-concept study
por: Lui, Natalie S., et al.
Publicado: (2022)

Coal Poised for a Comeback?
por: Fields, Scott
Publicado: (2004)

Telomere replication: poised but puzzling
por: Sampathi, Shilpa, et al.
Publicado: (2011)

'Atom-smasher poised for restart'
Publicado: (2009)

Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures
por: Comoglio, Federico, et al.
Publicado: (2018)

Optimizing ECG lead selection for detection of prolongation of ventricular repolarization as measured by the Tpeak‐end interval
por: Ruedisueli, Isabelle, et al.
Publicado: (2022)

Augmented Reality Based Navigation for Computer Assisted Hip Resurfacing: A Proof of Concept Study
por: Liu, He, et al.
Publicado: (2018)

Long-term results of excimer laser procedure to correct astigmatic refractive errors
por: Roszkowska, Anna M., et al.
Publicado: (2013)

Mapping chemical elements on the surface of orthodontic appliance by SEM-EDX
por: Mikulewicz, Marcin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9orhu3am0kth035gkcrbae6it7