The microRNA processing subunit DGCR8 is required for a T cell-dependent germinal center response

We have previously shown that the microRNA (miRNA) processor complex consisting of the RNAse Drosha and the DiGeorge Critical Region (DGCR) 8 protein is essential for B cell maturation. To determine whether miRNA processing is required to initiate T cell-mediated antibody responses, we deleted DGCR8...

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Detalles Bibliográficos
Autores principales: Daum, Patrick, Ottmann, Shannon R., Meinzinger, Julia, Schulz, Sebastian R., Côrte-Real, Joana, Hauke, Manuela, Roth, Edith, Schuh, Wolfgang, Mielenz, Dirk, Jäck, Hans-Martin, Pracht, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800915/
https://www.ncbi.nlm.nih.gov/pubmed/36591274
http://dx.doi.org/10.3389/fimmu.2022.991347

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