Cargando…

Up-regulation of Sirtuin-1/autophagy signaling in human cerebral ischemia: possible role in caspase-3 mediated apoptosis

AIM: Autophagy is a catabolic process, which plays a pivotal role in neuronal homeostases. Sirtuin-1 (Sirt1, Silent information regulator family protein 1) is a protein deacetylase that is activated by nicotinamide adenine dinucleotide (NAD(+)), is also influenced by starvation and stress response s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Teertam, Sireesh Kumar, Phanithi, Prakash Babu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801087/ https://www.ncbi.nlm.nih.gov/pubmed/36590507 http://dx.doi.org/10.1016/j.heliyon.2022.e12278

Ejemplares similares

Differential role of SIRT1/MAPK pathway during cerebral ischemia in rats and humans
por: Teertam, Sireesh Kumar, et al.
Publicado: (2021)

Roscovitine effectively enhances antitumor activity of temozolomide in vitro and in vivo mediated by increased autophagy and Caspase-3 dependent apoptosis
por: Pandey, Vimal, et al.
Publicado: (2019)

Cerebral ischemia induces TRPC6 via HIF1α/ZEB2 axis in the glomerular podocytes and contributes to proteinuria
por: Nakuluri, Krishnamurthy, et al.
Publicado: (2019)

Notch Signaling Suppresses Melanoma Tumor Development in BRAF/Pten Mice
por: Mikheil, Dareen, et al.
Publicado: (2023)

Buyang Huanwu Decoction promotes neurogenesis via sirtuin 1/autophagy pathway in a cerebral ischemia model
por: Li, Han, et al.
Publicado: (2021)

Sirtuin 1 Mediates Protection Against Delayed Cerebral Ischemia in Subarachnoid Hemorrhage in Response to Hypoxic Postconditioning
por: Diwan, Deepti, et al.
Publicado: (2021)

PIMT regulates hepatic gluconeogenesis in mice
por: Kapadia, Bandish, et al.
Publicado: (2023)

Autophagy Upregulation and Apoptosis Downregulation in DAHP and Triptolide Treated Cerebral Ischemia
por: Yang, Yang, et al.
Publicado: (2015)

Electroacupuncture Ameliorates Cerebral Ischemia-Reperfusion Injury by Regulation of Autophagy and Apoptosis
por: Shu, Shi, et al.
Publicado: (2016)

Sirtuin mediated neuroprotection and its association with autophagy and apoptosis: Studies employing transgenic C. elegans model
por: Nazir, Aamir, et al.
Publicado: (2013)

Apelin-13 inhibits apoptosis and excessive autophagy in cerebral ischemia/reperfusion injury
por: Shao, Zi-Qi, et al.
Publicado: (2020)

Dysregulated autophagy contributes to caspase-dependent neuronal apoptosis
por: Chung, Yuhyun, et al.
Publicado: (2018)

The Current State of Research on Sirtuin-Mediated Autophagy in Cardiovascular Diseases
por: Wang, Yuqin, et al.
Publicado: (2023)

Crosstalk Between Autophagy and Cerebral Ischemia
por: Sun, Yulin, et al.
Publicado: (2019)

Acupuncture protects against cerebral ischemia–reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis
por: Sun, Xiaowei, et al.
Publicado: (2020)

Sirtuin-3 activates the mitochondrial unfolded protein response and reduces cerebral ischemia/reperfusion injury
por: Xiaowei, Xie, et al.
Publicado: (2023)

Autophagy-competent mitochondrial translation elongation factor TUFM inhibits caspase-8-mediated apoptosis
por: Choi, Chang-Yong, et al.
Publicado: (2021)

SIGIRR-caspase-8 signaling mediates endothelial apoptosis in Kawasaki disease
por: Wen, Zhengwang, et al.
Publicado: (2023)

Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia-reperfusion rats
por: Shi, Cun-Xian, et al.
Publicado: (2020)

Caspases: A Molecular Switch Node in the Crosstalk between Autophagy and Apoptosis
por: Wu, Haijian, et al.
Publicado: (2014)

Novel functional roles of caspase-related genes in the regulation of apoptosis and autophagy
por: Shin, Ju-Hyun, et al.
Publicado: (2016)

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration
por: Chaitanya, Ganta Vijay, et al.
Publicado: (2010)

2-[2-(4-(trifluoromethyl)phenylamino)thiazol-4-yl]acetic acid (Activator-3) is a potent activator of AMPK
por: Bung, Navneet, et al.
Publicado: (2018)

Influence of Chronic Ethanol Consumption on Apoptosis and Autophagy Following Transient Focal Cerebral Ischemia in Male Mice
por: Li, Chun, et al.
Publicado: (2020)

Vagal Nerve Stimulation Protects Against Cerebral Ischemia–Reperfusion Injury in Rats by Inhibiting Autophagy and Apoptosis
por: Zhang, Li-Na, et al.
Publicado: (2021)

Telomerase confers resistance to caspase-mediated apoptosis
por: Bermudez, Yira, et al.
Publicado: (2006)

The Sirtuin-2 Inhibitor AK7 Is Neuroprotective in Models of Parkinson’s Disease but Not Amyotrophic Lateral Sclerosis and Cerebral Ischemia
por: Chen, Xiqun, et al.
Publicado: (2015)

Phospholipase D2 is a positive regulator of sirtuin 1 and modulates p53-mediated apoptosis via sirtuin 1
por: Lee, Hyesung, et al.
Publicado: (2021)

RNase L Cleavage Products Promote Switch from Autophagy to Apoptosis by Caspase-Mediated Cleavage of Beclin-1
por: Siddiqui, Mohammad Adnan, et al.
Publicado: (2015)

Surgically Induced Demyelination in Rat Sciatic Nerve
por: Rayilla, Rahul Shankar Rao, et al.
Publicado: (2023)

Computational research of Belnacasan and new Caspase-1 inhibitor on cerebral ischemia reperfusion injury
por: Li, Hui, et al.
Publicado: (2022)

Suppression of sirtuin 1 alleviates airway inflammation through mTOR-mediated autophagy
por: Wu, Yuanyuan, et al.
Publicado: (2020)

Sirtuin 4 activates autophagy and inhibits tumorigenesis by upregulating the p53 signaling pathway
por: Li, Juan, et al.
Publicado: (2022)

Aberrant Caspase Activation in Laminin-α2-Deficient Human Myogenic Cells is Mediated by p53 and Sirtuin Activity
por: Yoon, Soonsang, et al.
Publicado: (2018)

Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4
por: Kain, Vasundhara, et al.
Publicado: (2015)

Hydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen-activated protein kinase-caspase-3 signaling pathway following cerebral ischemia-reperfusion injury
por: Li, Da, et al.
Publicado: (2017)

Ischemia preconditioning is neuroprotective in a rat cerebral ischemic injury model through autophagy activation and apoptosis inhibition
por: Xia, D.Y., et al.
Publicado: (2013)

Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice
por: Deng, Changbo, et al.
Publicado: (2019)

let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3
por: Ham, Onju, et al.
Publicado: (2015)

Microvesicular Caspase-1 Mediates Lymphocyte Apoptosis in Sepsis
por: Exline, Matthew C., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dtqbg4frasp7512jbi0bgeajlp