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Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer

Malic enzymes (ME1, ME2, and ME3) are involved in cellular energy regulation, redox homeostasis, and biosynthetic processes, through the production of pyruvate and reducing agent NAD(P)H. Recent studies have implicated the third and least well-characterized isoform, mitochondrial NADP(+)-dependent m...

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Detalles Bibliográficos
Autores principales:	Grell, Tsehai A.J., Mason, Mark, Thompson, Aaron A., Gómez-Tamayo, Jose Carlos, Riley, Daniel, Wagner, Michelle V., Steele, Ruth, Ortiz-Meoz, Rodrigo F., Wadia, Jay, Shaffer, Paul L., Tresadern, Gary, Sharma, Sujata, Yu, Xiaodi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801130/ https://www.ncbi.nlm.nih.gov/pubmed/36590518 http://dx.doi.org/10.1016/j.heliyon.2022.e12392

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