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Hyaline Cartilage Microtissues Engineered from Adult Dedifferentiated Chondrocytes: Safety and Role of WNT Signaling
The repair of damaged articular cartilage is an unmet medical need. Chondrocyte-based cell therapy has been used to repair cartilage for over 20 years despite current limitations. Chondrocyte dedifferentiation upon expansion in monolayer is well known and is the main obstacle to their use as cell so...
Autores principales: | Kutaish, Halah, Bengtsson, Laura, Tscholl, Philippe Matthias, Marteyn, Antoine, Braunersreuther, Vincent, Guérin, Alexandre, Béna, Frédérique, Gimelli, Stefania, Longet, David, Ilmjärv, Sten, Dietrich, Pierre-Yves, Gerstel, Eric, Jaquet, Vincent, Hannouche, Didier, Menetrey, Jacques, Assal, Mathieu, Krause, Karl-Heinz, Cosset, Erika, Tieng, Vannary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801297/ https://www.ncbi.nlm.nih.gov/pubmed/36318262 http://dx.doi.org/10.1093/stcltm/szac074 |
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