PLK1 protects intestinal barrier function during sepsis by targeting mitochondrial dynamics through TANK-NF-κB signalling

BACKGROUND: Intestinal barrier integrity in the pathogenesis of sepsis is critical. Despite an abundance of evidence, the molecular mechanism of the intestinal barrier in sepsis pathology remains unclear. Here, we report a protective role of polo-like kinase 1 (PLK1) in intestinal barrier integrity...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Ying-Ya, Zhang, Yuan, Gerile, Wuyun, Guo, Yan, Wu, Li-Na, Wu, Li-Li, Song, Kai, Lu, Wei-Hua, Yu, Jian-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801534/
https://www.ncbi.nlm.nih.gov/pubmed/36581806
http://dx.doi.org/10.1186/s10020-022-00597-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801534/
https://www.ncbi.nlm.nih.gov/pubmed/36581806
http://dx.doi.org/10.1186/s10020-022-00597-z

Ejemplares similares